- βAID system users spent 6.5% more time in healthy blood sugar range β about 1.5 extra hours per day
- βThe AID system also reduced time spent too high or too low, and improved glucose stability
- βBoth devices were safe with no severe hypoglycaemia or diabetic ketoacidosis in either group
| Journal | Diabetologia |
| Year | 2024 |
| PMID | 38634887 |
What Was This Study About?
Researchers in South Korea compared two types of wearable, tubeless insulin pumps in adults with type 1 diabetes. One was an automated insulin delivery (AID) system β sometimes called a "closed-loop" or "artificial pancreas" system β that automatically adjusts insulin based on continuous glucose readings. The other was a sensor-augmented pump (SAP), which shows glucose data but requires the user to make manual adjustments.
Who Was Studied?
104 adults aged 19β69 with type 1 diabetes took part across 13 hospitals in South Korea. Half used the AID system and half used the standard sensor pump for 12 weeks. All participants had reasonably controlled diabetes at the start (HbA1c below 10%).
What Did They Measure?
The main goal was Time in Range (TIR) β the percentage of the day blood sugar stayed in a healthy zone (70β180 mg/dL). More time in range means better, more stable glucose control with fewer highs and lows.
Key Results
The AID group spent significantly more time in the healthy blood sugar range:
- AID system: TIR improved from 62.1% to 71.5% β a gain of nearly 10 percentage points
- Standard pump: TIR improved only slightly, from 64.7% to 66.9%
- The difference between groups was 6.5%, which is clinically meaningful (roughly 1.5 extra hours per day in range)
The AID group also had less time with blood sugar too high or too low, and more stable overall glucose levels.
What About HbA1c?
Both groups saw similar improvements in HbA1c (a 3-month blood sugar average), dropping to around 6.3β6.4% in both groups. The difference between the two groups was not statistically significant, suggesting both devices can support good long-term control.
Was It Safe?
Yes. There were no cases of diabetic ketoacidosis (DKA) or severe low blood sugar in either group throughout the 12-week trial.
What Does This Mean for Patients?
If you have type 1 diabetes and are considering an insulin pump, a tubeless AID system may offer better day-to-day glucose stability than a standard sensor pump β without the hassle of tubing. Talk to your diabetes care team about whether an AID system might be right for you.
